I'm having trouble configuring two infant and one toddler car seat in the Odyssey. Right now I have the toddler seat in the third row center and the two infant seats in the second row behind the driver and center (with the small middle seat removed). It's very difficult to buckle my toddler into the back, but if I leave the center aisle open I would end up leaving one of my newborns outside while I'm buckling in my toddler in the back. Does anyone have any better suggestions.

You didn't mention the year. But we have a similar setup. We took out the center console and moved the passenger seat over toward the middle. That gives an aisle along the passenger side. We put the 3yr old in the third row on the passenger side. The 2yr old behind the driver in the second row. And the 1yr old in the moved over passenger seat. The toddler can jump in and get in her seat and we can kneel in the aisle way to reach back and buckle her in.

Only bad thing is our 06 doesn't have the lower anchors in third row except the middle. So we had to use the seat belt. But we don't move it out often, so that isn't that big a deal.

I have the same setup right now in our 08, seats in the 2nd row are split and we have the oldest in a booster in the center 3rd row.

Come late December, early January, we will have two infant carriers, two Britax boosters, and one Britax toddler seat.

Buy Sunshine Kids car seats and stuff them all in the third row. That's what I do. If you have a need for a rear-facing car seat, I find that the Chicco has the most ergonomic design and narrowest base.

I blogged about three car seats in a single row here (http://www.csharpconsultant.net/post/2009/09/03/Three-Car-Seats-in-a-Prius-(or-Other-Mid-Sized-Car)-Easily!.aspx) back when we had three in a Prius. Now we have a fourth child on the way so we bought an Odyssey.